Enhancement of p38 MAPK signal mediated MutS homologue-2 (MSH2) expression in regulating gefitinib combinaned with metformin induced cytotoxicity in human lung squamous cancer cells
碩士 === 國立嘉義大學 === 生化科技學系研究所 === 102 === Gefitinib, a selective EGFR tyrosine kinase inhibitor, has a significant activity of the antiproliferative and proapoptotic both in vitro and in vivo. Human MutS homologue-2 (MSH2) plays a central role in promoting genetic stability by correcting DNA replicatio...
Main Authors: | Hsien-Chun Chiu, 邱憲君 |
---|---|
Other Authors: | Yun-Wei Lin |
Format: | Others |
Language: | zh-TW |
Online Access: | http://ndltd.ncl.edu.tw/handle/80535281304624510297 |
Similar Items
-
DNA Damage Induced MutS Homologue hMSH4 Acetylation
by: Chengtao Her, et al.
Published: (2013-10-01) -
MutS homologue hMSH5: role in cisplatin-induced DNA damage response
by: Tompkins Joshua D, et al.
Published: (2012-03-01) -
MutS homologue hMSH5: recombinational DSB repair and non-synonymous polymorphic variants.
by: Xiling Wu, et al.
Published: (2013-01-01) -
Characterization of Human and Mycobacterium tuberculosis mutY Homologues
by: Ho-Ting Su, et al.
Published: (1999) -
Up-regulated gene expressions of DNA mismatch recognition proteins MutS homolog 2 (MSH2) and MSH6 in zebrafish (Danio rerio) embryos after heat stress
by: Shin-Wei Chen, et al.
Published: (2012)