Modulation of Amidase to Develop New Dosage Forms of Anti-Tuberculosis Drugs without Hepatotoxicity and Application of Genetic Polymorphisms of Metabolic Enzymes in Early Diagnosis of Anti-Tuberculosis Drug-Induced Hepatotoxicity

博士 === 國防醫學院 === 生命科學研究所 === 102 === Anti-tuberculosis drug-induced hepatotoxicity (ATDIH) is the most common adverse drug reaction caused by first-line anti-TB drugs, i.e. isoniazid (INH), pyrazinamide (PZA) and rifampin (RIF). Among them, INH is the most potent single agent against TB but is also...

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Bibliographic Details
Main Authors: Hsin-Tien Ho, 何欣恬
Other Authors: Oliver Yoa-Pu Hu
Format: Others
Language:zh-TW
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/00168798383565075563