DNMT3L facilitates assembly of a repressive epigenetic modifying complex for retroviral silencing
博士 === 國立臺灣大學 === 生物科技研究所 === 102 === Mammalian genomes are replete with retrotranspoable elements including endogenous retroviruses. DNA methyltransferase 3-like (DNMT3L), an epigenetic regulator highly expressed in germ cells and embryonic stem (ES) cells, is crucial for the long-term suppression...
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| Format: | Others |
| Language: | en_US |
| Published: |
2014
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| Online Access: | http://ndltd.ncl.edu.tw/handle/08937437311945903829 |