TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation
博士 === 國立臺灣大學 === 分子醫學研究所 === 102 === The NLRP3 inflammasome, a multiprotein complex, triggers caspase-1 activation and maturation of proinflammatory cytokines IL-1β and IL-18 upon sensing a wide range of pathogen- and damage-associated molecules. Dyregulation of the NLRP3 inflammasome activity cont...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2013
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| Online Access: | http://ndltd.ncl.edu.tw/handle/71549307665243159802 |