A cell-based assay for identification of small chemical compounds that inhibit Supt4h/Supt5h protein complex formation

碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 102 === Huntington’s disease (HD) is an inherited neurological disorder caused by abnormal expansion of CAG repeats, which encode a long stretch of polyglutamine, in Huntingtin (HTT) gene. While the expression of mutant HTT contributes a gain-of-function for pathogen...

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Bibliographic Details
Main Authors: Yun-Yun Wu, 吳畇芸
Other Authors: Tzu-Hao Cheng
Format: Others
Language:zh-TW
Published: 2014
Online Access:http://ndltd.ncl.edu.tw/handle/55170386578516965082