Chemical and Enzymatic Synthesis of (S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol
碩士 === 長庚大學 === 生化與生醫工程研究所 === 103 === It is aimed to develop a competitive process for synthesizing (S)-5, 6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, an precursor of dorzolamide. At first, (S)-3-(2-thiophen-ylthio)butanoic acid, (S)-5,6-2H-6-methyl-thieno[2,3-b]-thiopyran-4-one, and (4R,6S)...
Main Authors: | , |
---|---|
Other Authors: | |
Format: | Others |
Published: |
2015
|
Online Access: | http://ndltd.ncl.edu.tw/handle/58750774047006463979 |