Alanine Scanning Mutagenesis of Aβ(17-42) Amyloid Fibril Stability by Molecular Dynamics Simulations
碩士 === 國立中央大學 === 化學學系 === 103 === Alzheimer’s disease (AD) is characterized by the extracellular deposit of senile plaques in the brain. Senile plaques are mainly composed of the aggregated amyloid beta (Aβ) protein called amyloid. Amyloid fibrils are semi-ordered nanostructures as the result of se...
| Main Authors: | , |
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| Format: | Others |
| Language: | en_US |
| Published: |
2015
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| Online Access: | http://ndltd.ncl.edu.tw/handle/xfnzx5 |