Antileukemia effect of halenaquinone, a protein kinase inhibitor, induced apoptosis via oxidative stress combined with inhibition of HDAC and topoisomerase activities

碩士 === 國立東華大學 === 海洋生物研究所 === 103 === Bioactivity-guided fractionation of the marine sponge of led to the isolation of marine polycyclic quinone-type metabolites, halenaquinone (HQ) and xestoquinone (XQ), which were found to inhibit a variety of cancer cell proliferation. The marine polycyclic quino...

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Bibliographic Details
Main Authors: Shou-Ping Shih, 施守平
Other Authors: Mei-Chin Lu
Format: Others
Published: 2015
Online Access:http://ndltd.ncl.edu.tw/handle/62867809568735708691