Toward Reducing Immunogenicity of Enzyme Replacement Therapy: Altering the Specificity of Human Beta-glucuronidase to Compensate for Alpha-iduronidase Deficiency
博士 === 國防醫學院 === 生命科學研究所 === 103 === Enzyme replacement therapy (ERT) is an effective treatment for many patients with lysosomal storage disorders (LSDs) caused by deficiency in enzymes involved in cell metabolism. However, immune responses that develop against the administered enzyme in some patien...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2015
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| Online Access: | http://ndltd.ncl.edu.tw/handle/25788432697294967196 |