The mechanism for thymidylate synthase-induced cellular transformation

碩士 === 國立陽明大學 === 生化暨分子生物研究所 === 103 === Thymidylate synthase (TS) plays a central role in the biosynthesis of dTTP. TS catalyzes the reaction of transferring a methyl group from 5,10-methylenetetrahydrofolate (meTHF) to dUMP for dTMP production. Elevation of TS is oncogenic and closely associated w...

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Bibliographic Details
Main Authors: Cheng-Wei Huang, 黃承煒
Other Authors: Zee-Fen Chang
Format: Others
Language:zh-TW
Published: 2015
Online Access:http://ndltd.ncl.edu.tw/handle/04118129540349529557