Dna-2 is a genetic modifier of the expended CUG repeats in C. elegans
碩士 === 國立中正大學 === 分子生物研究所 === 104 === Myotonic dystrophy type 1 (DM1) is a dominant neuromuscular disease caused by an expanded CTG repeat in the DMPK gene. The transcribed CUG repeats recruit the RNA binding protein, MBNL, to form RNA foci in the nucleus. This results in sequestration of MBNL and d...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | zh-TW |
Published: |
2016
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Online Access: | http://ndltd.ncl.edu.tw/handle/81614097240714961206 |