LKB1 Loss at transcriptional level Promotes Tumor Malignancy and Poor Patient Outcomes in Colorectal Cancer
博士 === 中山醫學大學 === 醫學研究所 === 104 === LKB1 loss by gene mutation, loss of heterozygosity, and promoter methylation was rarely occurred in colorectal cancer. The intracellular LKB1 kinase is implicated in regulating polarity, metabolism, cell differentiation, and proliferation – all functions potential...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2016
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Online Access: | http://ndltd.ncl.edu.tw/handle/90498844466606143293 |