LKB1 Loss at transcriptional level Promotes Tumor Malignancy and Poor Patient Outcomes in Colorectal Cancer

博士 === 中山醫學大學 === 醫學研究所 === 104 === LKB1 loss by gene mutation, loss of heterozygosity, and promoter methylation was rarely occurred in colorectal cancer. The intracellular LKB1 kinase is implicated in regulating polarity, metabolism, cell differentiation, and proliferation – all functions potential...

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Bibliographic Details
Main Authors: Tsung-Ying He, 何宗殷
Other Authors: Huei Lee
Format: Others
Language:en_US
Published: 2016
Online Access:http://ndltd.ncl.edu.tw/handle/90498844466606143293