Synthesis and Optimization of 2-(1-Ethyl-3,5-dimethyl-1H-pyrazol-4-yl)ethan-1-amine Derivatives with in Vitro Activity against Triple-Negative Breast Cancer Cells

碩士 === 國立中央大學 === 化學學系 === 104 === Triple negative breast cancer (TNBC) has high mortality rate, high recurrence and high brain metastasis. Chemotherapy is the only treatment, and the worst of all it develops drug resistance. Therefore, we devote to drug discovery and synthesis for alleviating the s...

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Bibliographic Details
Main Authors: Chia-Hui Lin, 林佳慧
Other Authors: Wen-Shan Li
Format: Others
Language:zh-TW
Published: 2016
Online Access:http://ndltd.ncl.edu.tw/handle/77382163953235178318