Delivery of antisense oligonucleotides specific to phosphodiesterase 4B gene by polyethylenimine downregulates LPS-induced TNF-α release in mouse macrophages
碩士 === 國立中央大學 === 生命科學系 === 104 === Phosphodiesterase 4B (PDE4B) is essential for various immune and inflammatory responses and hence plays important role in the pathogenesis of several inflammatory diseases. The nonselective PDE4 inhibitors, including the clinically approved roflumilast and apremil...
| Main Authors: | , |
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| Format: | Others |
| Language: | en_US |
| Published: |
2016
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| Online Access: | http://ndltd.ncl.edu.tw/handle/82776227143292084382 |