Design and synthesis of indole and indoline derivatives as a novel Src kinase inhibitor, a potential anti-cancer drug.

碩士 === 東海大學 === 化學系 === 104 === Src protein is a non-receptor tyrosine kinase and it plays a critical role in cell adhesion, invasion, proliferation, survival, and angiogenesis during tumor development. It was also found to be over-expressed and highly activated in a wide variety of human cancers, i...

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Bibliographic Details
Main Authors: Hsin-Chuan Kuo, 郭昕銓
Other Authors: Yu-Shan Wu
Format: Others
Language:zh-TW
Published: 2016
Online Access:http://ndltd.ncl.edu.tw/handle/72502966379763813967