Studies of Human Telomeric G quadruplexes: Molecular Mechanism of Drug Unbinding, Structural Conversion of Topoisomers and Hydration Shell Free Energy
博士 === 國立陽明大學 === 生命科學系暨基因體科學研究所 === 104 === Part I. Molecular Mechanism of Drug Unbinding from the Human Telomeric G quadruplex Human telomeres consist of tandem repeats of DNA sequence d[TTAGGG]. Inhibiting the activity of telomerase by formation and stabilization of G quadruplex has been reported...
Main Authors: | , |
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Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
2016
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Online Access: | http://ndltd.ncl.edu.tw/handle/34625928299550461392 |