Downregulation of caveolin-1 in keloid is responsible for cell softening and its mechanical activation of RUNX2 and excessive extracellular matrix production

博士 === 國立成功大學 === 臨床醫學研究所 === 105 === Keloids are pathologic scars and the exact pathogenesis remains unclear. Keloids are more likely to form in areas of the body subjected to increased skin tension or stiffness. We hypothesize that keloid results from the hyper-responsiveness of keloid fibroblasts...

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Bibliographic Details
Main Authors: Chao-KaiHsu, 許釗凱
Other Authors: Ming-Jer Tang
Format: Others
Language:en_US
Published: 2017
Online Access:http://ndltd.ncl.edu.tw/handle/sv9qkt