n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryprophan 2,3 dioxygenase in spinocerebellar ataxia type 3

博士 === 國立東華大學 === 生命科學系 === 105 === Spinocerebellar ataxia type 3 or Machado-Joseph disease (SCA3/MJD) is characterized by the repetition of a CAG codon in the ataxin-3 gene (ATXN3), which leads to the formation of an elongated mutant ATXN3 protein that can neither be denatured nor undergo proteolys...

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Bibliographic Details
Main Author: Karthyayani Rajamani
Other Authors: Tzyy-Wen Chiou
Format: Others
Published: 2016
Online Access:http://ndltd.ncl.edu.tw/handle/tfda5y