The molecular mechanisms of Sorafenib and GW5074 anti-cancer combination therapy in metastatic renal cell carcinoma

博士 === 國防醫學院 === 醫學科學研究所 === 105 === Mitochondria are the powerhouses of cells and targets of cancer therapeutics. The unique role of Raf proteins in the mitochondria provides a strong rationale to target mitochondrial Raf proteins. However, Raf inhibitor monotherapy induces serine 338 phosphorylati...

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Bibliographic Details
Main Authors: TSAI, YI-TA, 蔡易達
Other Authors: CHA, TAI-LUNG
Format: Others
Language:en_US
Published: 2017
Online Access:http://ndltd.ncl.edu.tw/handle/51617077893198827872