Development of Bacterial Beta-glucuronidase-specific Inhibitors to Reduce Chemo-induced Intestinal Toxicity and Prevent Tumorigenesis
博士 === 國立中山大學 === 生物醫學研究所 === 106 === Hepatic glucuronidation is a major route for detoxification. Drugs and carcinogens are conjugated with glucuronic acid to be inactive. However, the inactive glucuronides are reactivated back to active toxins by bacterial β-glucuronidase (βG) in the intestine, th...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2018
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| Online Access: | http://ndltd.ncl.edu.tw/handle/skc37g |