Caspase Cleavage of GFAP Produces an Assembly-Compromised Proteolytic Fragment that Promotes Filament Aggregation
博士 === 國立清華大學 === 分子醫學研究所 === 106 === Glial fibrillary acidic protein (GFAP) is the major constituent of the glial intermediate filaments that are expressed mainly in mature astrocytes of the central nervous system. Dominant mutations in the gene encoding GFAP cause Alexander disease, a primary gene...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | en_US |
| Published: |
2017
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| Online Access: | http://ndltd.ncl.edu.tw/handle/evxpx6 |