Development of potent and selective glycosidase inhibitors
博士 === 國立臺灣大學 === 化學研究所 === 106 === Glucuronidation is a major drug-metabolizing reaction in humans. Glucuronidated metabolites are hydrolyzed by intestinal bacterial β-glucuronidase (GUS) and release their toxic aglycones in intestines, resulting in intestinal damage. Diarrhea is a common dose-limi...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
2018
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| Online Access: | http://ndltd.ncl.edu.tw/handle/ya2uk2 |