The 3 +3 Design And Modified Toxicity Probability Interval Designs For The Maximum Tolerated Dose (MTD) In Phase I Clinical Trial

碩士 === 國立陽明大學 === 公共衛生研究所 === 106 === The widely used method is 3 + 3 design, because it is easy to understand and the implementation is quite simple. However, there is no possibility of finding the accurate maximum tolerated dose, since it is usually underestimated. Yuan Ji et al. in 2010 publ...

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Bibliographic Details
Main Authors: Fang-Yu Wen, 温芳羽
Other Authors: Yi-Hau Chen
Format: Others
Language:zh-TW
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/532b8e