CHK2-mediated Regulation of PARP1 in Oxidative DNA Damage Response

博士 === 國防醫學院 === 生命科學研究所 === 106 === Poly(ADP-ribose) polymerase 1 (PARP1) is a DNA damage sensor, which upon activation, recruits downstream proteins by poly(ADP-ribosyl)ation (PARylation). However, it remains largely unclear how PARP1 activity is regulated. Interestingly, the data obtained through...

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Bibliographic Details
Main Authors: Hsu, Pei-Ching, 徐珮菁
Other Authors: Shieh, Sheau-Yann
Format: Others
Language:en_US
Published: 2018
Online Access:http://ndltd.ncl.edu.tw/handle/346y29