Set-up of Compound Screening Platform for Identification of DNMT3A Demethylation Inhibitors

碩士 === 國立陽明大學 === 生命科學系暨基因體科學研究所 === 107 === DNA methylation and demethylation are critical for spatiotemporal modulation of gene expression. DNA methylation is generated by DNA methyltransferases, DNMTs, which can covalently add a methyl group to the 5-position carbon of cytosine (5mC). DNMTs are...

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Bibliographic Details
Main Authors: Yu-Chun Chen, 陳俞均
Other Authors: Che-Kun James Shen
Format: Others
Language:en_US
Published: 2019
Online Access:http://ndltd.ncl.edu.tw/handle/j2v994