Dysregulation of Galectin-3 causes neurotoxic phenotypes in the microglia of Huntington’s disease

博士 === 國立陽明大學 === 分子醫學博士學位學程 === 107 === Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder that manifests with movement dysfunction and cognitive decline. The disease-causing mutation is an expansion of CAG repeats in the Huntingtin gene. The resultant mutant Huntingtin (...

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Bibliographic Details
Main Authors: Jian Jing Siew, 蕭建靖
Other Authors: Yijuang Chern
Format: Others
Language:en_US
Published: 2019
Online Access:http://ndltd.ncl.edu.tw/handle/m5yw6n