Expression of human cystatin c by the methylotrophic yeast pichia pastoris
Human cystatin C is a cysteine-proteinase inhibitor with great potential as a therapeutic protein. The methylotrophic yeast, Pichia pastoris, was selected as a host to express a human cystatin C variant in which site directed mutagenesis was used to introduce two consensus sequences for N-linked...
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Format: | Others |
Language: | English |
Published: |
2009
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Online Access: | http://hdl.handle.net/2429/10460 |