Method development for the comprehensive analysis of post translational modifications by mass spectometry

Signal Transduction is mediated by protein complexes whose spatial- and temporal-distribution, composition and function within cells are often regulated by different post-translational modifications (PTM). As PTMs add or subtract a specific mass difference to a protein, mass spectrometry becomes ver...

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Bibliographic Details
Main Author: Hoffman, Michael David
Format: Others
Language:English
Published: University of British Columbia 2008
Subjects:
Online Access:http://hdl.handle.net/2429/1051