Molecular characterization of the ETV6-NTRK3 fusion in congenital fibrosarcoma

The t(12;15)(pl3;q25) rearrangement detected in congenital fibrosarcoma splices the ETV6 (TEL) gene on chromosome 12p13 in frame with the NTRK3 (TRKC) neurotrophin-3 receptor gene on chromosome 15q25. Resultant ETV6- NTRK3 fusion transcripts encode the helix-loop-helix (HLH) dimerization domain...

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Bibliographic Details
Main Author: Wai, Daniel Hon-Hei
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/10554