Stabilized antisense-lipid particles with enhanced intracellular delivery properties

Effective systemic delivery systems for DNA and RNA are essential to the successful clinical application of genetic drugs. Liposomal formulations of genetic drugs, such as antisense oligonucleotides (AS-ODN) and plasmid DNA, are difficult to achieve as the large size and highly charged nature of...

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Bibliographic Details
Main Author: Louie, Lenore Jennifer
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/10688