Biophysical characterization of catonic liposome/plasmid DNA complexes for gene therapy

The goal of gene therapy is to achieve expression of an exogenous gene that results in a specific functional change. Cationic liposome-based carriers of plasmid DNA ("lipoplexes") are the most widely used method of nonviral DNA delivery. Lipoplexes form through electrostatic interaction...

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Bibliographic Details
Main Author: Wasan, Ellen K.
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/10964