Modelling of voltage-dependent gating and sodium currents in the Kv1.5 potassium channel

Activation gating in voltage-gated potassium channels involves multiple closed-closed transitions prior to channel opening. We have examined various voltage-dependent properties of activation gating in the human Kvl.5 potassium channel heterologously expressed in HEK-293 cells. Two gating charge...

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Bibliographic Details
Main Author: Hesketh, John Christian
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/11306