Covalent catalyst in the UDP-glucose dehydrogenase

UDP-glucose dehydrogenase from Streptococcus pyogenes (EC 1.1.1.22) is a NAD ⁺- dependent enzyme that catalyzes the 4-electron oxidation of UDP-glucose to UDPglucuronic acid without the release of an aldehyde intermediate. This enzyme is interesting because its single active site carries out two...

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Bibliographic Details
Main Author: Ge, Xue
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/11419