Experimental diabetes in ß6 integrin deficient mice
Objectives: Periodontal disease involves transformation of the junctional epithelium (JE) to a pocket epithelium (PE). Integrin avß6 is constitutively expressed in the healthy IF but not in PE. Mice deficient of this integrin (ß6-/-) exhibit increased periodontal bone loss and PE migration. Thus, av...
| Main Author: | |
|---|---|
| Format: | Others |
| Language: | English |
| Published: |
University of British Columbia
2009
|
| Online Access: | http://hdl.handle.net/2429/14852 |