Ionomycin-induced activation of LFA-1 is independent of calpain-mediated cleavage of talin

Integrins are heterodimeric surface receptors that play a critical role in many cellular processes due to their ability to mediate the interactions between cells as well as between cells and the extracellular matrix. Integrin function can be regulated by conformational changes in their extracellular...

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Bibliographic Details
Main Author: Dreolini, Lisa Faye
Format: Others
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/16303