Dopamine trasporter reversal as a pathogenic mechanism for L-dopa induced dyskinesia
L-dopa remains the most effective drug for improving motor symptoms of Parkinson's disease (PD). However, following long-term chronic treatment, the therapeutic effects of L-dopa are often accompanied by debilitating peak-dose dyskinesia. The mechanisms underlying L-dopa induced dyskinesia r...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/16493 |