Quality filtering and normalization for microarray-based CGH data

Altered copy numbers of DNA sequences are a characteristic of solid tumors. Microarray-based Comparative Genomic Hybridization (CGH) has emerged as a promising technology that has the potential to identify minute genomic changes, in the order of single DNA copy number changes, at the gene level. The...

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Bibliographic Details
Main Author: Khojasteh Lakelayeh, Mehrnoush
Language:English
Published: 2009
Online Access:http://hdl.handle.net/2429/16526