Overexpression of NF-E2 related factor 2 via viral-mediated gene transfer in vivo.
The transcription factor NF-E2 related factor 2 (Nrf2) is responsible for the upregulation of the cellular anti-oxidant defence system. Upon stimulation by free radicals or reactive oxygen species (ROS), the cytoplasmic-bound Nrf2 translocates to the nucleus and initiates transcription of genes cont...
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| Language: | English |
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2009
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| Online Access: | http://hdl.handle.net/2429/16531 |