A wave-pinning mechanism for eukaryotic cell polarization based on Rho GTPase dynamics

In response to chemical stimulation, many eukaryotic cells are able to sense the direction of the stimulus and initiate movement. To do so, the cell must break symmetry and develop a front and back in a process known as polarization. During polarization, members of the Rho GTPase family (Cdc42,...

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Bibliographic Details
Main Author: Jilkine, Alexandra
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/17453