Opposing roles of NMDA receptor subtypes in neuronal fate and novel treatments for ischemic brain injury
Ischemic brain damage is largely due to excitotoxicity mediated by glutamate receptors, notably the N-methyl-D-aspartate-type receptors (NMDARs); however, to date none of the NMDAR antagonists have shown therapeutic benefits in treating stroke. Moreover, recent studies indicate blockade of NMDARs ma...
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| Language: | English |
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2010
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| Online Access: | http://hdl.handle.net/2429/18582 |