Nuclear localization and induction of rat hepatic drug metabolizing enzymes
The nucleus may be the critical site for the activation of chemical carcinogens, and subsequently the initiation of neoplasia. However, isolated nuclei may be contaminated with endoplasmic reticulum, the major site of the drug metabolizing enzymes. One of the objectives of the present study was to d...
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| Language: | English |
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2010
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| Online Access: | http://hdl.handle.net/2429/22783 |