Activity of and resistance to cationic antimicrobial agents in Pseudomonas aeruginosa

This thesis investigates mechanisms of adaptive resistance to the cationic antimicrobial agents tobramycin and polymyxin B in the opportunistic pathogen Pseudomonas aeruginosa. Using a comprehensive mutant library of P. aeruginosa to screen for genes capable of affecting tobramycin susceptibility, 1...

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Bibliographic Details
Main Author: Kindrachuk, Kristen Nicole
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/26798