Development of a ³²P-postlabeling assay for O⁶-methylguanine
Monitoring of the promutagenic DNA adduct, O⁶-methylguanine, in the exfoliated cells (e.g. oral mucosal) of tissues from individuals exposed to tobacco-specific N-nitrosamines may aid in the evaluation of tissue-specific risk of carcinogenesis. People with high levels of this adduct could be identif...
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| Language: | English |
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University of British Columbia
2010
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| Online Access: | http://hdl.handle.net/2429/27977 |