Model based approaches to array CGH data analysis

DNA copy number alterations (CNAs) are genetic changes that can produce adverse effects in numerous human diseases, including cancer. CNAs are segments of DNA that have been deleted or amplified and can range in size from one kilobases to whole chromosome arms. Development of array comparative gen...

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Bibliographic Details
Main Author: Shah, Sohrab P.
Format: Others
Language:English
Published: University of British Columbia 2008
Subjects:
HMM
Online Access:http://hdl.handle.net/2429/2808