Maternal-fetal disposition, fetal pharmacodynamics and comparative pharmacokinetics of diphenhydramine in pregnant and nonpregnant sheep

A capillary GC/NPD assay method which provides improved sensitivity and selectivity for diphenhydramine is reported. The assay method involves single drug extraction and splitless sample injection. Standard curves are linear in the range of 2-320 ng/mL of diphenhydramine, which represents an amount...

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Bibliographic Details
Main Author: Yoo, Sun Dong
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/29325