Short-read DNA sequence alignment with custom designed FPGA-based hardware

The alignment of short DNA read sequencing data to a human reference genome sequence has become a standard step in the analysis pipeline for short DNA read sequence data. As the rate at which short read DNA sequence data is being produced doubles every 5 months, analysis of this data in a computatio...

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Bibliographic Details
Main Author: Hall, Adam
Language:English
Published: University of British Columbia 2010
Online Access:http://hdl.handle.net/2429/30008