Novel pathways in fatty-acid induced apoptosis in the pancreatic beta-cell

Pancreatic β-cell death is a critical event in the pathogenesis of all forms of diabetes. Type 2 diabetes is caused by the combination of acquired factors such as elevated circulating fatty acids as well as genetic factors. In this study, we show that the free fatty acid palmitate increases marke...

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Bibliographic Details
Main Author: Jeffrey, Kristin Danielle
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/31378