Synthesis of UDP-6-deoxy-6,6-difluoro-D-GlcNAc : a potential mechanism-based inhibitor of pseB

Pseudaminic acid is a nine carbon sugar, similar to sialic acid, and has been found to play an important role in the biosynthesis of flagella in pathogenic bacteria such as C. jejuni and H. pylori. For these bacteria the flagella is crucial in motility and colonization of the host. Because this s...

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Bibliographic Details
Main Author: Bassiri, Jackie Mehrnaz
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/31825