NMDA receptor desensitization regulated by direct binding to PDZ1-2 domains of PSD-95

Regulation of NMDA receptor (NMDAR) activity by desensitization is important in physiological and pathological states; NMDAR desensitization contributes in shaping synaptic responses and may be protective by limiting calcium influx during sustained glutamate insults. We previously reported that g...

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Bibliographic Details
Main Author: Sornarajah, Lavan
Language:English
Published: University of British Columbia 2011
Online Access:http://hdl.handle.net/2429/32400