Development of novel peptides for blocking aggregation and caspase-3 cleavage of TDP-43
TAR DNA-binding protein 43 (TDP-43) is a protein that is thought to be involved the pathology of amyotrophic lateral sclerosis (ALS) and frototemporal lobar degeneration (FTLD). Several TDP-43 mutations have been found in sporadic and familial ALS and FTLD. In patients with these neurodegenerative d...
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| Language: | English |
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University of British Columbia
2011
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| Online Access: | http://hdl.handle.net/2429/33548 |